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Additional advantages include less blood sampling (analysis is performed on the same EDTA sample used for full blood count analysis) and reduced cost compared to traditional measures (74% cost saving in our center)

The mutant proteins typically retain their transcriptional activity but have lost their KEAP1-binding capacity, meaning that they overcome KEAP1-mediated inhibition and KEAP1-triggered ubiquitylation

Mirrakhimov , Moonis Mirza , Maryam Mirzaei , Roya Mirzaei , Awoke Misganaw , Sanjeev Misra , Prasanna Mithra , Chaitanya Mittal , Javad Moghadasi , Ashraf Mohamadkhani , Abdalla Z

Surgical treatment of hepatocholangiocarcinoma: a systematic review

These effects are central to the classification of necroptosis as an immunogenic cell death (ICD) modality (45)