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Clinical trials showed modest fat loss of roughly 2-3 kg over 12 weeks, and the compound was never approved as a pharmaceutical because efficacy did not meet the threshold for drug registration (Heffernan et al., 2001)

Here, we synthesize these findings into a cohesive model of a bidirectional vicious cycle that amplifies neuropathology and drives the progression of depressive disorders (Figure 3)

Salehi B, Mishra AP, Nigam M, Sener B, Kilic M, Sharifi-Rad M, Fokou PVT, Martins N, Sharifi-Rad J (2018) Resveratrol: a double-edged sword in health benefits

The renal parameters of mice were evaluated by measuring hematocrit and renal clearance of 51Cr-EDTA at 20, 25, and 32 weeks after WBI with 240 kVp X-rays (1030 Gy in 2 fractions)

Herbert MR, Ziegler DA, Deutsch CK, Obrien LM, Lange N, Bakardjiev A, Caviness VJ (2003) Dissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boys