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IGF-1R inhibition may therefore activate the IR pathway by shunting IGF-mediated signaling through the IR

Targeting amyloid-beta precursor protein, APP, splicing with antisense oligonucleotides reduces toxic amyloid-beta production

Finally, to assess a functional indicator of oxidative damage and mitochondrial reactive oxygen species production, the activity of aconitase, a redox-sensitive enzyme in the tricarboxylic acid cycle, was measured

The difficulty of establishing the efficacy of bronchodilators in this heterogeneous population is further exemplified by the premature termination of a recent major clinical trial (111)

People with alcohol use disorder tend to be deficient in riboflavin and thiamine, another B-vitamin