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Hyaluronidase activity and AQP2/creatinine ratio were measured in urine every 60 minutes after water loading test by turbidimetric assay and ELISA, respectively

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The potentially beneficial features of IgE include its affinity for the FcR, expressed by the immune effectors responsible for ADCC and ADCP, and the low levels of normal IgE in the blood, which avoids competition with the therapeutic IgE

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Extrapolating this to a 70kg human using the standard FDA allometric scaling factor (dividing by 6.2) suggests a human-equivalent dose of approximately 8mg/kg, or 560mg daily
