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Ion intake, transit, and storage are coordinated by ion channels and transporters in the mitochondrial and plasma membranes

Following injury, the elevated levels of ROS and the consequent oxidative stress are considered critical events associated with the secondary injury progression [102]

Rare anaphylactoid symptoms (facial pallor, blood pressure drop) may occur, so monitor the patient closely, and avoid nerves and blood vessels during IM injection

They are involved in metabolism, skin health, immune and nervous system functions, muscle tone and the prevention of anemia

Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single centre, phase 2 pilot trial