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Preclinical models In vitro experiments Cell culture and protein extraction Primary human adult kidney fibroblasts from a single donor (DV Biologics, AU009-F) were cultured in 10% FCS low-Glucose DMEM with 1% Pen/Strep antibiotics (Sigma)

It is also used to treat migraine headaches and schizophrenia

Moreover, during CRPC progression, FOXA1 frequently undergoes somatic alterations, some of which can advance the progression of CaP and activate a CaP-specific AR-driven oncogenic transcriptional program [70, 71]

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