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Efforts are ongoing to develop synthetic derivatives of scopoletin and to characterize and improve its bioavailability and pharmacokinetic properties (96)

We discovered SnCE1 having an autoacetyltransferase (AcT) activity and confirmed earlier reports stating its weak DUB activity, cleaving Lys11-, Lys48- and Lys63-linked Ub chains but acting as an efficient deSUMOylase 26

Apr 22;2019 J Athl Train

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155157 One mechanism by which cholesterol likely drives these processes is through its role in determining the physical properties of the cell surface
