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When Se deficiency occurs in the context of already existing hypothyroidism, the symptoms of myxedema (such as puffiness of the skin, a hoarse voice, and slowness of mental function) may become more pronounced [73]
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doi: 10.1016/j.biopha.2019.108690 206 SahmFOezenIOpitzCARadlwimmerBVon DeimlingAAhrendtTet al
10.1002/14651858.CD006612.pub4 Cochrane Database Syst Rev
