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Description
Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea
Pfizer and OPKO did not state the reasons for the initial denial
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While BDNF requires continuous presence to maintain synaptic effects, Dihexa initiates structural changes that persist after compound clearance
These cohorts are evidence but the design constraints are significant and need to be stated plainly: The studies are not blinded, randomized, placebo-controlled trials by Western regulatory standards
