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When you run low, the result is often a stubborn, draining sort of tiredness that no amount of coffee seems to fix
This in turn is reliant on certain enzymes (acetlyases and methylases), which are directly controlled by various nutrients, in particular the B vitamins
To obtain the concentration-response curves, serially diluted agonists were added to each well to stimulate the cells
J Appl Physiol 106:98895
