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They cause an imbalance between specific groups of bacteria and trigger the development of dysbacteriosis (Tulstrup et al., 2015)

However, it exhibits low cell membrane permeability and demonstrates substantial toxicity in animal models, thereby constraining its potential application as a therapeutic agent (Zweygarth et al., 1986)

The recommended dietary allowance (RDA) of vitamin B12 during pregnancy is 2.6 mcg, and for breastfeeding women, it is 2.8 mcg

Administration routes in these studies include intraperitoneal injection, intragastric (oral) gavage, and topical application as a thin cream layer, with the choice of route depending on the experimental model