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In this study, we used LOXL2 as a representative member of the LOX family for proof of concept and validation assays because LOXL2 has recently garnered notable interest as a target in fibrosis and vascular aging 12,15,16

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Currently, the neuroprotective potential of these supplements has only been examined separately in studies

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These complex and reciprocal interactions have been termed dynamic reciprocity, and highlight the importance of the ECM in tissue and organ physiology (Cox and Erler, 2014)

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