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ROS production, mitochondrial membrane potential, mitochondrial fusion and fission, and mitophagy also function in ferroptosis

However, at concentrations of 10 -6 M, 10 -5 M, and 10 -4 M, cell viability was significantly reduced ( Supplementary Figure S4A )

However, given that mRNA levels of myelin proteins are reduced at 1 week, when oligodendrocyte death is ongoing, the lower synthesis may be a consequence rather than a driver of oligodendrocyte toxicity (Fig