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It is synthesized in keratinocytes and is highly upregulated in psoriatic skin [94] and epithelial skin tumors [95]

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Indirect human data: Growth hormone studies show bone and cartilage benefits

Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan oligosaccharides

Oral versions exist, but absorption is inconsistent when youre trying to treat joint tissue specifically