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In contrast, Gepon exposure only caused minimal and statistically insignificant increases in SMAD2 phosphorylation, suggesting that it does not effectively trigger the canonical pathway

When exposed to the peptide, fibroblasts and keratinocytes produce more collagen and elastin, extracellular matrix proteins

Research background matters because peptide handling, sequence stability, and route-specific formulation all affect interpretation

Discussion RBCs maintain homeostasis despite constant exposure to reactive oxygen species both in vivo and during blood bank storage, but the mechanistic details of how RBCs protect themselves from oxidative damage are incompletely defined [34]

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