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It is made up of three types of molecules known as amino acids, and it plays an important role in keeping us healthy

This can result from chronic oxidative stress, heavy metal toxicity (especially iron overload), persistent infections, nutrient insufficiencies (sulfur amino acids, glycine, glutamate, selenium, B-vitamins), liver dysfunction, metabolic stress, and genetic polymorphisms in key enzymes like glutamate-cysteine ligase (GCL) or glutathione S-transferases (GSTs)

These two genes, together with environmental factors, partly explain the interindividual variation in warfarin dose requirements