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The combination of GIP and GLP-1 activation creates a synergistic effect that neither pathway achieves alone, which explains why tirzepatide outperforms semaglutide in head-to-head comparisons

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274 Additionally, the size of the older adult population is expected to continue to increase relative to the population age 64 and younger a shift known as population aging due to a projected decline in fertility, as well as to increased survival at older ages

It puts a little bit of a strain on us for sure, but we have-- we've been on the phone for at least the last hour and a half, and I was emailing people last night

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