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In addition, once MODS develops, the gut is continuously injured by a combination of factors intrinsic to critical illness (dysbiosis, ischemia, etc.) and unintended consequences of interventions not aimed at the gut but that injure components of the gut (proton pump inhibitors, antibiotics, opioids, etc.)

American journal of obstetrics and gynecology 184, 12781283 (2001)

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