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In hypogonadal men with diabetes or in male rodents with androgen deficiency, decreased mitochondrial density, abnormal mitochondrial morphology, and lower ATP production were observed, while exogenous testosterone supplementation effectively alleviated mitochondrial dysfunction and improved glucose and lipid metabolism ( 2 The sex-dimorphic regulatory impact of androgens and AR on glucose and lipid metabolism 2.1 Inhibited androgens/AR negatively affects glucose and lipid metabolism in males The most well-known androgens include testosterone, androstenedione, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and dihydrotestosterone (DHT)

Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China

Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans

These findings suggested a shared molecular mechanism underlying the lifespan-enhancing effects of these diets

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