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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have a reliable hypoglycaemic and weight-loss effect that can intervene in obesity, which is the basis of type 2 diabetes pathology

Thyroid markers and tirzepatide: the calcitonin question Every tirzepatide label carries a black box warning about medullary thyroid carcinoma (MTC)

This underscores the therapeutic potential of enhancing the functionality of the antioxidant axis to treat UC targetting ferroptosis ( Nrf2 /GPX4 signaling, increasing GPX4 activity, inhibiting ferroptosis, and improving intestinal barrier integrity ( Nrf2 /GPX4 signaling, increase GPX4 activity, inhibit ferroptosis, and treat UC ( In summary, drugs can upregulate the content of GSH and GPX4 through various signaling pathways, thereby treating UC by inhibiting ferroptosis and promoting antioxidation

In the execution phase of apoptosis, a highly conserved family of proteins, the caspases (cysteine proteases), play an important role