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Cytokines modulate steroidogenesis and can skew estrogen-progesterone ratios, which changes menstrual flow, length, and symptom burden

(A,E) Lower face width (mm) assessed by Visia 7 (cross-polarized light) showing facial contour changes over time

An open-label study with etanercept revealed no efficacy in the treatment of moderate to severe alopecia areata 167

doi:10.1016/j.fufo.2025.100680 174
