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This apparent lack of a global reactive astrogliosis response was not anticipated based on prior studies using a controlled cortical impact paradigm to induce TBI

The baffling aspect of this disease is the great heterogeneity of response among patients, ranging from severe symptoms to asymptomatic progression

The phenolic hydroxyl group contributes additional hydrogen bonding capacity, while the aliphatic chain increases hydrophobic character relative to shorter peptide analogues

Tadros M, Forouhar F, Wu GY

This radical/non-radical dichotomy of ROS is essential because it maps directly onto their divergent spatial and kinetic behaviors