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February 12: Out of the first 7.5 million doses administered from Dec 14- Jan 18, 19 cases of anaphylaxis were reported to VAERS after the Moderna vaccine

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| | Intensive Performance Protocol | 10mg subcutaneous, 5x/week (weekdays) | 150mg oral, daily | Both compounds AM, pre-training | 6 weeks on, 4 weeks off | Athletic performance research, substrate utilization studies, endurance capacity trials | Higher dosing frequency and dose intensity produce more pronounced short-term shifts in RER and VO2 max, but require stricter adherence and increase washout sensitivity

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In a head-to-head trial against liraglutide, tirzepatide reduced measured food intake and craving more despite lower GLP-1 occupancy