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In contrast, under antioxidant/low-ROS conditions (such as in certain tumor microenvironments or after treatment with BPC157 in our study), BACH1 becomes stabilized and can switch to promoting angiogenesis by directly activating target genes like VEGF

10.1016/j.lfs.2015.09.012 52

doi: 10.1016/j.bbrc.2016.08.178

Lung cellular and molecular physiology 2007

Melatonin antagonizes Mn-induced oxidative injury through the activation of keap1-Nrf2-ARE signaling pathway in the striatum of mice
