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[] Primary cancer prevention is to diminish the likelihood of cancer development by eradicating or reducing exposure to risk factors and encouraging healthy practices

Although CCT expression is enhanced by diverse transcription factors such as E2F (72) that is regulated by IGF1 stimulation (60), we do not discard other possible mechanisms triggered by IGF1R nuclear localization to justify the higher expression of CCT detected in U87WT cells

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doi: 10.3389/fceld.2025.1628470 Received 14 May 2025 Accepted 09 October 2025 Published 20 October 2025 Volume 4 - 2025 Edited by Paola Maycotte, Instituto Mexicano del Seguro Social, Mexico Reviewed by Walaa Keshk, Tanta University, Egypt Victor E