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Potentially, yes
In addition, rather than leading to an increase in rT3 levels directly caused by an imbalance in DIO3, the available data imply that Se deficit may indirectly cause these levels to rise via reduced clearance of DIO1 and changes in peripheral thyroid hormone metabolism [33]
PMID: 188 Levi MorteraSMarzanoVVernocchiPMatteoliMCGuarrasiVGardiniSet al
That role is real and well described in biochemistry
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