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This percentage is comparable with studies on KD for PDHC deficiency (13/19 = 68%) [26] or epilepsy with mitochondrial dysfunction (22/34 = 65%) [12, 17]

Peripheral blood mononuclear cells (PBMC) were isolated by leukapheresis and stored in liquid nitrogen

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The expression of genes related to DNA damage was changed in the cartilage of KBD patients 130,131