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Even though the pathophysiology of these conditions is well understood, it has not been adequately translated into effective treatments to stop or reverse the course of the disease ( One of the key challenges in developing effective therapies against NDs is the blood-brain barrier (BBB) which is very selective hence, hinders the delivery of therapeutic agents to the brain ( Recent breakthroughs in nanotechnology have provided novel approaches for overcoming the BBB

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[DOI] [PMC free article] [PubMed] [Google Scholar] Kaplowitz N, Aw TY, Ookhtens M

The function of ROS can be either beneficial or damaging, depending on its cellular concentration and localization 2,3,4

Optimization of Fluorescence Derivative Method for Determination of Sulfur Dioxide Residues in Sulfur-fumigated Dangshen and Its Decoction Pieces by Response Surface Analysis