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However, it is not clear whether they regulate the expression of SLC7A11

Vaporciyan AA, Rice D, Correa AM, Walsh G, Putnam JB, Swisher S, Smythe R, Roth J

Oxidative stress happens when unstable molecules called free radicals outnumber protective antioxidant molecules in the body

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No significant change in cortical bone volume was observed in the conditional knockouts compared to controls, possibly due to the fact that the trabecular compartment undergoes the highest rate of remodeling during the time of observation (Zhang et al., 2002)