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Aspiration to check whether the needle is in a blood vessel is not necessary (PHE, 2013)

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Any use outside the stated research purpose is strictly prohibited.

A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy

specifically, the deletion (null) genotypes of GSTM1 and GSTT1 significantly increase PD risk, and a combined deletion further heightens this association (188)