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Collectively, our findings unveil the previously unrecognized function and significance of the CDK4/6-DUB3 axis in stabilizing YAP1 and provide a rationale for potential therapeutic interventions in the treatment of HCC

Studies have shown that miR-27a-3p, miR-675, miR-145, miR-25, miR-340, miR-330-5p, miR-211, miR-155, miR-218, miR-21a-5p8, and other miRNAs affect melanogenesis through various mechanisms (175)

In tumors with overactivated PI3K/AKT/mTOR pathways, artemisinin and EGCG demonstrate multitarget regulatory advantages

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Zhang Y, Xie L, Ding X, Wang Y, Xu Y, Li D, et al