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Gut Health Support: Your gut plays a bigger role in hormone regulation than most people think

The needle should be inserted at a 90-degree angle for most patients, though very thin individuals may need to use a 45-degree angle or pinch the skin to ensure subcutaneous rather than intramuscular injection

K.WenderN.HegermannJ.BrunnerB.et al (2010)

In the Phase II trial, 73% to 94% of participants reported side effects with retatrutide, especially at the higher doses of 8 mg and 12 mg once weekly