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CGRP is a powerful vasodilator, with a long-lasting effect on bronchial vessels and this is evident in vitro and in vivo

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Clinically, late-phase pain often becomes dissociated from inflammation and resistant to anti-inflammatory therapies, resembling NPP

The G6PD-d HUVECs also demonstrated increased expression of VCAM/ICAM-1, TGF and other pro-inflammatory molecules such as TNF and MCP-1
