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Furthermore, the mutator phenotype associated with defective MutL activity was suppressed when a non-functional recB allele, derived from ET-37 meningococcal strains, replaced the functional recB allele, suggesting that in MutL-deficient strains, hypermutation mostly arises during post-replicative DNA synthesis associated with the activity of the RecBCD recombination pathway ( N

He was an advocate for the preservation of rural landscapes in the San Dieguito River valley, served on the Del Mar Mesa Community Planning Board for more than 10 years, and chaired the Los Peasquitos Canyon Preserve Citizens Advisory Committee