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In a study on long-term compliance with antioxidants to prevent GC, it was confirmed that the compliance of antioxidants with GC is negatively correlate 26

2018;13(8):e0201369

Chlorogenic acid inhibited APAP-induced activation of caspase-3 and caspase-7, JNK, ERK1/2, and upstream molecular signaling of p38 MAPKs in animals, including apoptosis signal-regulated kinase 1 (ASK1), c-Raf, and Mitogen-activated protein kinases MEK1/2, MKK3/6 and MKK4 (Ji et al., 2013), thereby inhibiting apoptosis

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upon binding, the histone termini can be buried snugly into a shallow pocket, which greatly facilitates the overall affinity [53]