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Free Radical Biol Med 15:435445 Gomberg M (1900) An instance of trivalent carbon: triphenylmethyl
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Researchers utilize animal studies in vivo to study PD through comprehensive approaches that monitor how PD affects neuronal circuits along side glial interplay and whole body processes [76]
It was demonstrated that in the spinal cord of the SOD1-G93A ALS mouse model, the mitochondrial receptor SQSTM1/p62 is recruited to the mitochondrial surface, where it activates mitophagy, whereas knockdown of the Parkin gene reduces the loss of motor neurons, thereby delaying the progression of disease in SOD1-G93A mice (Palomo et al., 2018)
