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SCFAs (notably butyrate, propionate, and acetate) are increasingly recognized as signaling metabolites with immunometabolic effects relevant to neurovascular integrity (

We employ industry-leading High Performance Liquid Chromatography and Liquid/Gas Chromatography-Mass Spectrometry in our manufacturing pipeline, and routine analyses are conducted in a CLIA environment using a flexible range of Thermo Scientific and Agilent modalities

Human NAT2 is a xenobioticmetabolising enzyme that provides a major route of detoxification of drugs such as isoniazid (an antituberculotic drug), hydralazine and endralazine (antihypertensive drugs), a number of sulphonamides (antibacterial drugs) (Kawamura et al., 2005), procainamide (antiarrhythmic drug), aminoglutethimide (an inhibitor of adrenocortical steroid synthesis), nitrazepam (a benzodiazepine) and the antiinflammatory drug dapsone (Ginsberg et al., 2009, Butcher at al., 2002)

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Exploring the Functional Consequences of Protein Backbone Alteration in Ubiquitin through Native Chemical Ligation