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The absence of FDA approval means no verified manufacturing standards, dosing protocols, or safety benchmarks exist for human use

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Chiral selectivity underpins thousands of biological processes, including enzyme-substrate catalysis, redox reactions, signal transduction, control of amino acid synthesis and tRNA folding, ribosomal protein formation, nucleic acid identification, transcription and translation, metabolite interactions with cell signaling pathways, and other activities ( 2 Factors that catalyze chiral discrimination of 2-hydroxyglutarate Our primary focus in this review is the study of aberrant growth of 2-hydroxyglutarate (2HG) (C 5 H 8 O 5

Journal (Journal of Physiology and Pharmacology, Dec 2009, 60 Suppl 7, 191196)

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