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Following this, for every individual subject, the placement of the MRS voxel was applied as a 20 20 20 mask (individually measured for each subject based on 1H-MRS acquisition) to the three respective tissue maps providing a segmentation quantity for each tissue in the specific 1H-MRS voxel placement

Consequently, the question of whether spermatogenic impairment in 5-reductase-2 deficient males is a direct result of the gene mutation or a secondary consequence of incomplete testicular descent remains open