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Following from previous work that sought to identify sequence determinants of S fibrillation, a library-based -lactamase tripartite fusion construct in which S was inserted between Blac fragments and probed for aggregation, identified mutations within the P1/P2 regions that impacted on the ability of S to aggregate

Investigation, A.B

By unlinking bioidentical hormones from the catastrophic warnings previously associated with older, synthetic progestins and conjugated equine estrogens, the FDA is empowering physicians to treat the "whole patient." We are moving away from addressing only the most severe vasomotor symptoms and toward a model of long-term health maintenance

Moreover, it remains unclear why equal decreases occur in nuclei [173]

10.1186/s12866-017-1096-1 164