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There is no established upper limit for B12 intake due to its low risk of toxicity

A 2025 wave of social-media posts even flagged mislabeled vials and dose errors in this exact compound
Vegetarians and vegans, since B12 is primarily found in animal-based foods, may experience a deficiency that can become significant over time

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Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those using diuretics concomitantly and the elderly
