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Cell 172, 389390

Spermidine/spermine N (83)

Other studies have reported correlations between genotype and activity (157, 301) or between selenium and GPx-1 activity (285, 355)

From an immunological perspective, these associations arise from a breakdown in self-tolerance mediated by overlapping T-cell and B-cell autoreactivity, shared cytokine pathways (e.g., IFN-, IL-18), and common antigen-presenting HLA alleles

In 1937, the protein was first crystallized from bovine liver at Sumner and Dounce's laboratory [13]
