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SnRK2.1 and SnRK2.2 regulates the expression of stress-related genes and decreases osmotic tolerance, but the regulatory relationship between the activated SnRK2s and stress-related gene expression remains to be identified (Yang et al., 2015)

PLOS ONE 10 , e0117772 (2015)

Genetic polymorphisms in genes coding for enzymes, receptors, and transporters related to opioid disposition (pharmacokinetics) and pharmacology (pharmacodynamics) are well documented.169 Examples include pharmacogenetics of various enzymes, such as cytochrome P450s and uridine diphosphoglucuronosyltransferases, opioid receptors, and the ABC family of transporters

Moreover, NEIL1 deficient cells were resistant to psoralen + UVA damage, and had a faster rate of psoralen removal, hinting on a negative role of NEIL1 in the repair of ICLs

Many highly effective chemotherapeutic agents, such as oxaliplatin, cisplatin, and docetaxel, cause severe, dose-limiting nerve damage as a side effect