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Differently, curcumin seems to directly stimulate the secretion of glucagon-like peptide-1 by activating the Ca2+/calmodulin-dependent kinase II pathway (independently of the cAMP/PKA pathway) (Takikawa et al., 2013)

To assess the contribution of these adaptors to TBK1 activation by TLR3, we next investigated poly(I:C)-induced TBK1 activation in triple knockout (TKO) cells lacking these three adaptors

doi: 10.3389/fphar.2014.00124 71 RamakrishnanSKShahYM
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Aziz M, Brenner M, Wang P
