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No noteworthy adverse effects were noted in both studies
Acid-degradable core-shell nanoparticles for reversed tamoxifen-resistance in breast cancer by silencing manganese superoxide dismutase (MnSOD)
Lv et al., 2022)
notably described that the substitution of the first 290 residues of MRP1 by the corresponding residues of MRP2, like in chimera M1, leads to a complete absence of addressing to the plasma membrane with a retention in the endoplasmic reticulum 19
[DOI] [PubMed] [Google Scholar] 69.Bilton D., Daviskas E., Anderson S.D., Kolbe J., King G., Stirling R.G., et al
