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doi: 10.1016/j.phymed.2024.156195 29 GessnerA.di GiuseppeR.KochM.FrommM

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L-Carnitine supports efficient fat metabolism by transporting fatty acids into muscle mitochondria for energy production

PGC-1 attenuates inflammation through suppression of NF-B signaling and NLRP3 inflammasome activation, linking mitochondrial function to inflammatory control [126,127,128]

A recent trial showed that the combination of nortriptyline and gabapentin at the maximum tolerated dose was more effective than either monotherapy despite a lower maximum tolerable dose as compared with monotherapy 218