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Palmieri EM, et al

Nature 475 , 9195 (2011)

Reduced blood flow limits the availability of vital nutrients and hydration to the muscles, hindering their optimal performance and making them more susceptible to cramps and spasms

The presence of comorbidities can significantly impact the pharmacokinetics of Vitamin B12, making it essential to adjust dosing protocols. Expert Opinion on Vitamin B12 Therapy Genetic Factors Affecting B12 Metabolism Genetics play a role in how well someone can use Vitamin B12