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Genetics also appear to play a role as the PNPLA3-I148M variant may not only modify lipid droplet metabolism but have a direct role on stellate cell function in NASH (103)

Ferroptosis can be experimentally induced by direct inhibition of Gpx4 via Ras-selective lethal small molecule 3 (RSL3) or by genetic knockdown or deletion of Gpx4 (Yang et al., 2014)

Alzheimers disease: diverse aspects of mitochondrial malfunctioning

Primary hypothyroidism can present with hyperprolactinaemia, which is reversible with thyroid hormone replacement