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2020 (ASCO guideline): Based on the above evidence, the American Society of Clinical Oncology recommended in 2020 that clinicians DISCOURAGE use of acetyl-L-carnitine for preventing chemotherapy-related nerve damage [29]

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Longo N., di San Filippo C.A., Pasquali M

Participants received 20, 40 or 60 mg/kg/d or placebo and it was reported that the 60 mg/kg/d treatment was discontinued due to it exacerbating the ataxia symptoms in 2 patients (Pandolfo et al., 2014)

Fatty acid oxidation-driven Src links mitochondrial energy reprogramming and oncogenic properties in triple-negative breast cancer