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In contrast, at least 1 of the folate receptors, FR-, is expressed in hematopoietic cells and the kidney proximal tubules, among other tissues (Table 2)

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Additionally, ethanol induces the rapid synthesis of stress proteins in young animals [71, 72] while production of stress proteins is diminished in aging animals [73-75]

R-ALA is significantly more bioavailable and biologically active than the S-form, which is why high-quality supplements typically specify the use of R-ALA.